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In the United States, chronic infection with hepatitis B occurs in approximately 5 to 10 percent of individuals with acute hepatitis B infection. Chronic infection ranges in presentation from the asymptomatic carrier to the patient with active chronic infection. Diagnosis of chronic infection is based on serology showing the persistence of hepatitis B surface antigen (HBeAg) for more than six months.
When a patient is diagnosed with chronic hepatitis B infection, it is important to counsel them that their household members and intimate contacts should be screened and, if found susceptible, vaccinated.
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